Bie van wiele tielt heeft bij routine klinisch onderzoek bij een hond testis knobbels gepalpeerd. It is the most common cancer in men aged 1544 years. Detection of occult primary tumors in patients with metastatic germ cell tumors17 or unex. Tumor limited to testis and epididymis without vascularlymphatic invasion. We report a case of a newborn with a prenatal diagnosis of scrotal mass. Unduh sebagai doc, pdf, txt atau baca online dari scribd. Due to the rarity of these tumors, exact etiology, pathogenesis, prognostic factors. While most adult gcts are benign, those that present with distant metastases manifest a grave prognosis. Kepaniteraan klinik tht rumah sakit umum daerah karawang fakultas kedokteran universitas trisakti periode 8 oktober 9 november 2012 lembar pengesahan 1 nama.
This process is experimental and the keywords may be updated as the learning algorithm improves. Well circumscribed, slow growing, non invasive, non metastatic. Tumor testis biasanya berkembang selama masa pubertas, walaupun beberapa penelitian menyatakan tumor berkembang sebelum usia 10 tahun. Yolk sac tumor has also been known over the years as endodermal sinus tumor, juvenile embryonal carcinoma, embryonal adenocarcinoma, distinctive adenocarcinoma of the infant testis, testicular adenocarcinoma with clear cells, and orchioblastoma,14,15,16,17,18 current evidence has. Myoid gonadal stromal tumor of the testis is an uncommon spindle cell tumor hypothesized to arise from peritubular myoid cells or intertubular primitive mesenchymal cells.
The rete testis radiates from the mediastinum testis to the surface of the tunica. The adult type of granulosa cell tumor is extremely rare in the testis 46 cases have been described to date table 31. Approximately 56% of all testis tumors are nongerm cell tumors of the testis. The remaining 60 patients were treated with high inguinal orchiectomy. Unduh sebagai pptx, pdf, txt atau baca online dari scribd. There is evidence that the size of primary tumor, infiltration of.
Germ cell tumors of the testis tumors of the testis health. Testicular cancer is the most common malignancy that develops in men between the ages of 20. The testis is surrounded by the tunica albuginea, which has low t1 and t2 signal intensity. Seminoma is the most common germ cell tumor in bilateral primary testicular tumors, while malignant lymphoma is the most common bilateral tumor of the testis. Neonatal testicular tumors are rare and should be considered in the differential diagnosis of newborn scrotal masses. There are about 2,000 new cases in the uk each year.
Leydig cell tumors see the image below are derived from normal leydig cells that produce testosterone and are located in the interstitium of the testis. Around half of all cases occur in men aged under 35 but testicular cancer rarely occurs before puberty. Insiden tumor testis pada populasi umum adalah satu dari 100. Start studying medical terminology ch9 male reproductive system. Testicular tumors are uncommon in children, comprising approximately 1% to 2% of all pediatric malignancies 14. Introductio testicular conclusion n torsion introduction. Louis, mo, usa department of pathology, washington university school of medicine, st. For a scrotal mass it is difficult to distinguish a benign or malignant etiology, in addition to the origin whether from testis or epididymis. Sertoli cell tumors of the testis are uncommon sex cord stromal tumors. Metastatic leydig cell tumor of the testis report of three. The presence of a hydrocele may delay the diagnosis of a testis tumor, and an ultrasound scan should be considered for any boy with a hydrocele in which the testis cannot be palpated. A leydig cell tumor of the testis is an uncommon testicular neoplasm. Testicular cancer is a cancer that arises from a testicle testis. Pathology outlines mixed unclassified sex cord stromal.
Histologically, reinkes crystals and capsular invasion by tumor cells were found. Epidemiology may present in both pediatric and adult males, depending on the histologic subtype. According to ajcc, tumors confined to testis without lymph node involvement are stated as stage i. Primary bilateral tumors of the testis may happen synchronously or asynchronously but tend to be of the same histologic type. Diagnosis is typically based on a physical exam, ultrasound, and blood tests.
Alive dead alive or dead without tumor total from tumor other cause total per cent total 51 24 27 24 3 27 52. Granulosa cell tumor gst is a sexcordstromal neoplasm of the gonads, more commonly arising in the ovaries, while approximately 80 cases have been reported in the testes. Stefanie angeline 04084821719171 siti evi marissa 04054821719116 supervised by. Tumor may invade tunica albuginea but not tunica vaginalis. Tumor testis berasal dari sel germinal atau jaringan stroma testis.
The size of the tumor in the testis is irrelevant to staging. In nonneoplastic testicular tissue, the seminiferous tubules showed sertoli cells with complete spermatogenesis, hematoxylineosin stain x10 b. Terletak didalam scrotum dengan axis panjang pada sumbu vertikal dan biasanya testis kiri terletak lebih rendah dibanding kanan. Anatomi dan fisiologi testis merupakan sepasang struktur organ yang berbentuk oval dengan ukuran 4x2,5x2,5cm dan berat kurang lebih 20g. Myoid gonadal stromal tumor american journal of clinical. In the current study, only one case had a tumor that was less than 2 cm.
Case report metastatic granulosa cell tumor of the testis. However, the incidence of testicular tumors in children is increasing, and associated morbidity has doubled during the last 40 years 4, 5. Education exhibits 665 mr imaging of scrotal tumors and. In the prepubertal testis tumor registry, 11% of patients had a hydrocele at presentation, which may have been secondary to the tumor or coincidental.
Cancer survival among adults us seer program, 19882001. Ileri evre testis tumorunde, international germ cell cancer. Abstract a rare case of malignant sertoli cell tumor of the testis occurred in which the diagnosis was initially suggested on fine needle aspiration cytology. Alphafetoprotein afp is a tumor marker that is elevated in 6070% of patients with hepatocellular carcinoma. After surgery, the histological diagnosis was juvenile granulosa cell tumor. Options that have been employed in previous cases include retroperitoneal lymph node dissection rplnd. Malignant mesothelioma of the tunica vaginalis testis. The patient characteristics are age, race, and sex. Ppt referat torsio testis free download as powerpoint presentation. May 10, 2017 testicular sex cord stromal tumors include leydig cell tumors, sertoli cell tumors, and granulosa cell tumors. Learn vocabulary, terms, and more with flashcards, games, and other study tools.
Not well organized, irregularly shaped, fast growing, infiltrative growth, metastatic. The tumor characteristics may include subsite, size of tumor, extension of the tumor, lymph nodes positive, distant metastases, and histologic type. Tumor ini mempunyai derajat keganasan tinggi, tetapi dapat sembuh bila diberi penanganan adekuat. Initial stages of malignant cancer may typically show benign growth. Juvenile granulosa cell tumor jgct accounts for about 5% of all prepubertal testis tumors. Tumor testis merupakan keganasan terbanyak pada pria berusia diantara 1535 tahun dan merupakan 12% dari semua neoplasma pada pria.
Intratubular germ cell neoplasia carcinoma in situ in situ, intraepithelial, noninvasive. The incidence testicular of torsion in males younger urological torsion is a. The most common presentation is a scrotal mass of variable duration. Referat primery bone tumors benign tumor neoplasms. Granulosa cell tumors gcts of the testis are rare sex cordstromal tumors that are present in both juvenile and adult subtypes. Its imaging appearance on ultrasound and mri is nonspecific, but clinically it is associated with serum hormonal imbalance. Tumor primer testis bilateral dapat terjadi secara berbarengan ataupun tidak, tetapi cenderung memiliki kesamaan jenis histilogisnya. Microscopically, the uninvolved parenchyma of the right testis showed fig. Risk factors include an undescended testis, family history of the disease, and previous history of testicular cancer. Current experience on sertoli cell tumor of the testis sctt is insufficient to prognosticate the clinical behavior of the primary tumor on the long. A malignant leydig cell tumor of the testis springerlink. Leydig cell tumor is the most common stromal tumor of the testis, followed by sertoli cell tumors. Epididimitis atau pembengkakan epididimis lain, hidrokel, atau tumor testis tidak memberikan sensasi khas itu. Dec 29, 2014 more recently, testis sparing surgery has been suggested as a safe and efficacious choice for patients with a testicular tumor of its diameter less than 2 cm.
Other types include sexcord stromal tumors and lymphomas. Leydig cell carcinoma is relatively refractory to radiotherapy and chemotherapy, and median survival of patients with metastatic disease is less than 2. Testicular sex cord stromal tumors include leydig cell tumors, sertoli cell tumors, and granulosa cell tumors. Ratarata 10% dari tumor testis berasal dari undesensus testis.
Guidelines for the diagnosis and staging of testicular cancer. Traditionally limbic encephalitis was considered in the context of a tumour paraneoplastic di sease with onconeuronal antibodies against in tracellular proteins. Oncotesticular sperm extraction oncotese from a single. Scribd is the worlds largest social reading and publishing site. Whereas granulosa cell tumors are typical for the ovaries.
Epididymal inflammatory myofibroblastic tumor, also known by various other synonyms is a rare benign disease. Germ cell tumors of the testis tumors of the testis. Figenshau 1 division of urologic surgery, washington university school of medicine, st. Ultrasound images of the scrotum showed an eccentric, predominantly hypoechoic vascular mass in the posterior aspect of the right testis measuring 2.
Erasmus, 2006 netherlands pmid 17158533 controversies in the management of clinical stage i testis cancer. Nov 11, 2008 epididymal inflammatory myofibroblastic tumor, also known by various other synonyms is a rare benign disease. A 40yearold man was referred to our hospital with gynecomastia and painless swelling of the right scrotum. Sertoli cell tumor of the testis sertoli cell testicular. Malignant germ cell tumor composed of primitive epithelial tumor cells recapitulating early stages of embryonic development. Tumor testis free download as powerpoint presentation. U, mars surgery departement faculty of medicine sriwijaya university rsup dr. Adult type granulosa cell tumor of the testis with a. Due to the rarity of these tumors, exact etiology, pathogenesis, prognostic factors and best treatment approach are not well known.
Testis diliputi oleh tunika albuginea pada 23 anterior kecuali pada sisi dorsal dimana terdapat. In terms of occurrence patterns, oncotese in testicular cancer can be categorized into three types. Most common patterns are microfollicular and diffuse other patterns trabecular. Testicular yolk sac tumors account for 70% to 80% of prepubertal malignant testicular tumors and are the most common. The latter mostly concerned infants and followed a benign course. Testicular cancer is categorized as being in one of three stages which have subclassifications.
Treatments for aggressive gcts are not well established. Mixed germ cell tumour of infantile testis showing. Radiation oncologytestisoverview wikibooks, open books. The most common type is germ cell tumors which are divided into seminomas and nonseminomas. Out of these, 30 cases were of the adult type, while the remainder 50 cases were of the juvenile type. Download as doc, pdf, txt or read online from scribd. Primary neuroendocrine tumor of the testis article pdf available in urology annals 62. As a benign neoplasm, radical orchiectomy is sufficient for treatment. The incidence testicular of torsion in males younger urological torsion is a emergency. A rare case of primary carcinoid tumor in otherwise mature teratoma of the testis which occurred in a 70yearold male is reported. Granulosa cell tumor of testis is a rare tumor accounting for less than 4% of adult testicular tumors though they account for nearly 30% of childhood testicular tumors. In 2009, it was found in 2570 cases of malignant primary bone tumor, and 1470 of them died because this disease. Three types will be considered, namely, leydig cell tumors, sertoli cell tumors, and gonadoblastomas.
Adult granulosa cell tumor of the testis masquerading as. Oncotesticular sperm extraction oncotese for bilateral. Nongerm cell tumors of the testis tumors of the testis. Leydig cell tumor of the testis radiology reference article. They are less common than leydig cell tumors of the testis. Leydig cell tumor of the testis radiology reference.
Clinical presentation and management anandmohapatra, 1 aaronm. Testicular cancer urology associates of northeast florida. Diagnosis alphafetoprotein afp alphafetoprotein levels may be assessed by a blood test. In broad terms, testicular cancer is staged as follows. The majority of patients with prepubertal testis tumors present with stage i disease80% in the prepubertal testis tumor registry. Jika tumor testis sekunder disingkirkan maka insiden tumor testis primer bilateral 1 2,8 % dari seluruh kasus tumor sel germinal testis. Testicular tumor undescended testis testicular torsion granulosa cell tumor leydig cell tumor these keywords were added by machine and not by the authors. The mediastinum testis has signal intensity similar to that of the testis on t1weighted images and is lower in signal intensity than the testis on t2weighted images.
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